Aleva Neurotherapeutics
Implantable MEMS‑based directional deep brain stimulation (DBS) system improving precision and outcomes in Parkinson’s and essential tremor.
Switzerland
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Neuromodulation
Amber Therapeutics
Developing an adaptive, implantable neuromodulation device for women’s mixed urinary incontinence.
UK
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Neuromodulation
Ampa Health
Developing a portable transcranial magnetic stimulation system to expand access to clinically validated neuromodulation treatments for mental health disorders.
USA
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Neuromodulation
BRAIN.Q
Developing non-invasive, AI-driven neuromodulation systems to promote neuroplasticity and functional recovery after neurological injury.
Israel
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Neuromodulation
BrainsWay
Developing non-invasive deep transcranial magnetic stimulation systems for the treatment of psychiatric and neurological disorders.
Israel
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Neuromodulation
Cala Health
Pioneering wearable, wrist-based neuromodulation (TAPS) to reduce essential tremor by delivering patient-specific stimulation to the median and radial nerves.
USA
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Neuromodulation
Cefaly
Delivering FDA-cleared, over-the-counter external trigeminal nerve stimulation to acutely treat and prevent migraines without drugs.
Belgium
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Neuromodulation
Clarity
Developing a non-invasive headset using 40 Hz light and sound stimulation to restore brain rhythms in Alzheimer’s and related disorders
USA
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Neuromodulation
Cognito Therapeutics
Evoking gamma brain waves via light and sound headset to slow Alzheimer’s progression, slowing cognitive decline, atrophy, and functional loss.
USA
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Neuromodulation
Fisher Wallace Labs
Offering an FDA-cleared cranial electrotherapy stimulator that non-invasively treats depression, anxiety, and insomnia via home use.
USA
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Neuromodulation
Flow Neuroscience
Delivering a portable tDCS headset that gently stimulates the prefrontal cortex to relieve depression symptoms, med-free, at-home therapy.
Sweden
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Neuromodulation
Galvani Bioelectronics
Developing implantable bioelectronic therapies to modulate organ-specific nerve signals (e.g. splenic nerve) for chronic disease treatment.
UK
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Neuromodulation
GrayMatters Health
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Developing Prism, an FDA-cleared neurofeedback system using EEG-based biomarkers to train self-regulation of brain networks in PTSD and depression.
Israel
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Neuromodulation
Grey Matter Neurosciences
Developing portable, focused ultrasound headset to non‑invasively stimulate deep brain circuits and improve cognition in Alzheimer’s disease.
Canada
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Neuromodulation
Inner Cosmos
Developing an implantable digital neuromodulation system to deliver precision brain stimulation for the treatment of depression.
USA
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Neuromodulation
Magnus Medical
Developing SAINT®, an image-guided, accelerated, non-invasive neuromodulation system targeting personalized brain networks to treat severe depression.
USA
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Neuromodulation
Marbles Health
Offering portable, hospital‑grade non‑invasive neuromodulation (tES + EEG + cognitive training) to support recovery from mental health and neuropsychiatric conditions.
India
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Neuromodulation
Motif Neurotech
Developing minimally invasive, battery-free brain implants (DOT) that wirelessly stimulate brain circuits to treat treatment-resistant depression.
USA
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Neuromodulation
Nalu Medical
Developing an implantable neuromodulation system with a miniaturized, battery-free architecture for chronic pain and neurological conditions.
USA
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Neuromodulation
NeuraWorx
Developing bioelectronic neuromodulation technologies to enhance cerebral waste clearance by modulating cerebrovascular dynamics and glymphatic system function.
USA
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Neuromodulation
NeuralPulse
Creating implantable adaptive neuromodulation that probes brain responses, predicts seizures, and delivers responsive stimulation to prevent them.
UK
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Neuromodulation
Neuraura
Developing wearable bioelectronic devices combining micro-electrodes and stimulation to relieve PCOS symptoms and enhance personalized chronic care.
Canada
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Neuromodulation
NeuroEM Therapeutics
Developing wearable head devices delivering transcranial electromagnetic treatment (TEMT) for Alzheimer’s and related dementias.
USA
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Neuromodulation
NeuroOne
Developing thin-film implantable electrodes to enable high-precision neural recording, stimulation, and ablation in neurosurgical and neurological care.
USA
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Neuromodulation
NeuroSigma
Developing non-invasive trigeminal nerve stimulation devices to treat pediatric ADHD and other neurological conditions.
USA
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Neuromodulation
Neuroacoustics
Using non-invasive acoustic stimulation during sleep to modulate brain oscillations and improve cognition, neurological health, and sleep quality.
USA
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Neuromodulation
Neuroelectrics
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Providing Starstim and Enobio devices for wireless EEG monitoring and non-invasive brain stimulation, applied in research, clinical trials, and therapy.
Spain
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Neuromodulation
Neurolief
Delivers wearable, at-home neuromodulation via Relivion, stimulating multiple cranial nerve branches to relieve migraine and depression.
Israel
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Neuromodulation
Neuromod
Developing non‑invasive bimodal neuromodulation device (Lenire) combining tongue and audio stimulation to reduce tinnitus symptoms.
Ireland
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Neuromodulation
Neuronoff
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Developing a minimally invasive, needle-delivered neuromodulation electrode platform to expand access to peripheral nerve stimulation for chronic pain treatment.
USA
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Neuromodulation
Neuros Medical
Developing an implantable neuromodulation system to treat chronic pain by blocking pain signals in peripheral nerves.
USA
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Neuromodulation
Neurovalens
Developing FDA-cleared, non-invasive vestibular neurostimulation wearables (Modius Sleep, Modius Stress) to treat insomnia, anxiety, and metabolic disorders.
UK
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Neuromodulation
Neuspera
Developing a wirelessly powered implantable neuromodulation system for treating pelvic health and chronic neurological conditions.
USA
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Neuromodulation
Nexstim
Developing navigated transcranial magnetic stimulation systems for non-invasive brain mapping and neuromodulation in clinical and research settings.
Finland
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Neuromodulation
Nia Therapeutics
Delivering personalized closed‑loop deep brain stimulation via implantable neuromodulation to counter memory loss in TBI and cognitive disorders.
USA
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Neuromodulation
Noctrix Health
Developing non-invasive neuromodulation therapies to treat chronic neurological and sleep-related conditions using targeted peripheral nerve stimulation.
USA
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Neuromodulation
Nyxoah
Developing an implantable neuromodulation system to treat obstructive sleep apnea by stimulating the hypoglossal nerve.
Belgium
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Neuromodulation
Onward Medical
Developing implantable and non-invasive neuromodulation systems to restore movement and autonomic function after spinal cord injury.
Netherlands
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Neuromodulation
Openwater
Developing wearable, open-source infrared and ultrasound platforms to diagnose and non-invasively treat diseases such as stroke, depression, and tumors.
USA
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Neuromodulation
Precisis
Developing a minimally invasive neuromodulation system to treat drug-resistant focal epilepsy through targeted brain stimulation.
Germany
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Neuromodulation
Presidio Medical
Developing a closed-loop spinal cord stimulation system designed to deliver adaptive neuromodulation for chronic pain management.
USA
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Neuromodulation
QV Bioelectronics
Developing GRACE, an implantable electric field therapy (EFT) device for glioblastoma treatment, targeting tumor cells post-resection to slow recurrence and extend survival.
UK
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Neuromodulation
Reach Neuro
Developing implantable spinal cord stimulation systems (Avantis) that restore voluntary upper-limb movement in chronic stroke survivors.
USA
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Neuromodulation
Salvia BioElectronics
Developing an implantable neuromodulation system to treat chronic migraine by modulating neural pathways involved in pain processing.
Netherlands
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Neuromodulation
Samphire Neuroscience
Pioneering a wearable brain-first neurotechnology, Nettle, that provides non-hormonal brain stimulation to reduce menstrual pain, low mood, and brain fog.
UK
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Neuromodulation
Sharper Sense
Developing a wearable, non-invasive neck patch that stimulates sensory-enhancing neural circuits to improve hearing, vision, and touch in real-time.
USA
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Neuromodulation
Sinaptica Therapeutics
Delivers personalized, closed-loop rTMS-EEG neuromodulation (SinaptiStim) targeting the default mode network to slow Alzheimer's progression with Phase 2 clinical efficacy.
USA
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Neuromodulation
SonoMind
Developing non-invasive focused ultrasound neuromodulation to precisely stimulate deep brain regions for the treatment of drug-resistant depression.
France
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Neuromodulation
Sooma Medical
Providing a portable tDCS-based neuromodulation system for depression and chronic pain, enabling remote clinician management and scalable home treatment.
Finland
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Neuromodulation
Spark Biomedical
Developing FDA-cleared, wearable, non-invasive auricular neurostimulation (Sparrow Ascent) to provide drug-free relief for opioid withdrawal and other conditions.
USA
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Neuromodulation
Spinally
Developing FuturaLead, the world’s first intrathecal spinal cord stimulation (iSCS) lead, placed directly on the spinal cord surface, enabling superior efficacy and closed-loop neuromodulation via ECAP sensing.
Spain
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Neuromodulation
SpineX
Delivering non-invasive spinal cord neuromodulation therapies (SCONE™, SCiP™) to treat neurogenic bladder, cerebral palsy, and related neurological impairments.
USA
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Neuromodulation
Synergia Medical
Developing optoelectronic, MRI‑compatible vagus nerve stimulator (NAO.VNS) to safely treat drug‑resistant epilepsy via long‑life, fast‑charge implant.
Belgium
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Neuromodulation
Syntropic
Using 60 Hz non-invasive light stimulation via the eyes to trigger microglia-mediated neuroplasticity, offering a fast, drug-free option for depression and brain recovery.
Austria
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Neuromodulation
Test startup
This is a test
Austria
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Neuromodulation
Theranica
Offering Nerivio, a wearable, smartphone-controlled neuromodulation arm band that delivers drug-free, FDA-cleared relief and prevention for migraines.
USA
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Neuromodulation
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