Samphire Neuroscience develops wearable neurotechnology designed to address menstrual-related symptoms through non-hormonal brain stimulation. The company’s flagship device, Nettle, is positioned as a brain-first approach to managing menstrual pain, low mood, and cognitive symptoms. Its platform focuses on influencing central neural processes rather than targeting peripheral symptoms alone. Samphire Neuroscience positions its technology within applied neuroscience and women’s health contexts.

The technology delivers non-invasive brain stimulation through a wearable device, with protocols designed to modulate neural circuits associated with pain perception and mood regulation. Stimulation sessions are intended to be brief and repeatable, supporting use during specific phases of the menstrual cycle. The approach does not rely on hormonal intervention, focusing instead on neuromodulatory mechanisms. The system emphasizes usability and comfort to enable regular, at-home use.

Samphire Neuroscience targets individuals seeking non-hormonal options for managing menstrual pain and associated cognitive or emotional symptoms. The platform is positioned outside traditional pharmaceutical treatment pathways and is intended to complement existing self-care strategies. Its focus reflects growing interest in brain-based approaches to women’s health that address cyclical neurological and emotional changes.