STARTUP PROFILE

Cognito Therapeutics

COUNTRY
USA
FOUNDED
2016
CATEGORY
Neuromodulation
Evoking gamma brain waves via light and sound headset to slow Alzheimer’s progression, slowing cognitive decline, atrophy, and functional loss.
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Neurofounders Insights
$   Funding   -
Series C+
MODALITY
Light/sound
FORM FACTOR
Headset/cap
INTERFACE DEPTH
Non-invasive
INDICATION
Dementia/impairment
TARGET USER
Patients
REGULATORY STAGE
Investigational
Cognito Therapeutics is one of the most advanced companies in the gamma entrainment space, with clinical evidence suggesting disease-modifying effects in Alzheimer’s. Its Series C+ funding and clinical progress position it as a leading non-invasive therapeutic contender, though long-term efficacy remains under investigation.
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MOST RECENT COVERAGE
#
5
New Clearances and Stronger Coverage
7 July – 21 July 2026

Cognito Therapeutics presented new biomarker data from its Phase 2 study at the Alzheimer's Association International Conference. The findings show that daily use of Spectris, its non-invasive sensory stimulation headset, increased cerebrospinal fluid levels of several HDL-like lipid transport proteins in patients with amyloid-positive mild cognitive impairment. The company reads the data as a coordinated biological response. The data are exploratory but reinforce a proposed mechanism for the gamma-frequency approach. A full data readout is expected next month.

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Cognito Therapeutics