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The Startup Map
An interactive database of neurotech startups worldwide, from brain-computer interfaces and neuromodulation to neuroimaging and cognitive health tools. Updated monthly, the map makes it easy to explore emerging companies, track novel technologies, and discover new innovations shaping the future of brain technology.
Developing cloud-native infrastructure and APIs that enable brain-computer interface developers to collect, train, and deploy neural data applications securely and at scale.
Building foundation models for brain data that decode thoughts into text, images, and speech from non-invasive neural recordings including EEG and fMRI.
Developing a fully digital Alzheimer’s therapy that uses ultra-high-frequency digital-photonic stimulation via the retina, delivered through VR/AR, to activate memory systems.
Building open-source neurotechnology tools and standards that make advanced brain-computer interfaces accessible to researchers, developers, and creators worldwide.
Developing wearable, open-source infrared and ultrasound platforms to diagnose and non-invasively treat diseases such as stroke, depression, and tumors.
Developing the Connexus, a fully implantable, high–data-rate BCI that records single-neuron brain signals to restore communication in paralyzed patients.
Developing the Layer 7 Cortical Interface, a minimally invasive, high-resolution brain–computer implant to restore communication and independence via thought.
Developing biological foundation models and clinical research platforms to understand, detect, and prevent neurological disease through AI-driven neuroscience.
Empowering imaging teams with a cloud-native AI platform that automates MRI data upload, biomarker extraction, and centralized review for clinical trials.
Developing the Delphi-MD, a first-in-class TMS-EEG functional neuroimaging system for early detection and differential diagnosis of brain disorders at the point of care.
Developing GRACE, an implantable electric field therapy (EFT) device for glioblastoma treatment, targeting tumor cells post-resection to slow recurrence and extend survival.
Developing non-invasive neuromodulation systems that combine transcranial electrical stimulation with immersive VR/XR software to support neurorehabilitation workflows.
Developing an implantable cortical visual prosthesis that converts camera input into patterned stimulation of the visual cortex to restore functional vision.
Providing a cloud-based AI platform (StrivePD) that transforms smartphone and wearable neurology data into actionable insights for precision neurology.
Develops invasive brain-machine interface systems for reconstructive therapy, aiming to restore neural control in conditions unresponsive to conventional options.
Developing the Evoke System, the first FDA-approved closed-loop spinal cord stimulation system using evoked compound action potentials (ECAPs) to automatically adapt therapy in real time.
Pioneering a wearable brain-first neurotechnology, Nettle, that provides non-hormonal brain stimulation to reduce menstrual pain, low mood, and brain fog.
Delivering a wearable audiovisual neuromodulation mask that uses light and sound pulses via HRV feedback to reduce chronic pain, improve sleep, and ease anxiety.
Developing a wearable, non-invasive low-intensity focused ultrasound platform targeting the splenic nerve and autonomic neural pathways for treatment of chronic inflammatory diseases.
Developing an implantable peripheral nerve stimulation system (SENSY) that provides sensory feedback to amputees, allowing them to feel their prosthetic limbs.
Developing Clotild, a smart guidewire using impedance-based microsensors and AI to characterize vascular tissue and aid intraoperative decision-making in stroke treatment.
Offering enterprise-ready AI voice biomarker SDKs for passive health monitoring across mental, cognitive, and respiratory wellbeing via everyday voice.
Providing a portable tDCS-based neuromodulation system for depression and chronic pain, enabling remote clinician management and scalable home treatment.
Developing FDA-cleared, wearable, non-invasive auricular neurostimulation (Sparrow Ascent) to provide drug-free relief for opioid withdrawal and other conditions.
Developing FuturaLead, the world’s first intrathecal spinal cord stimulation (iSCS) lead, placed directly on the spinal cord surface, enabling superior efficacy and closed-loop neuromodulation via ECAP sensing.
Developing the Sprint PNS System, an FDA-cleared temporary implantable peripheral nerve stimulation device for drug-free treatment of chronic and post-surgical pain.
Building miniaturized, wireless, battery-free BCI chips enabling simultaneous stimulation and recording across multiple brain regions for future therapies.
Developing a non-invasive neuromodulation system using peripheral nerve stimulation to modulate supraspinal circuits for overactive bladder and related chronic indications.
Providing AI-powered enhancements for MRI and PET scanning, boosting image clarity, reducing scan time, and enabling dose minimization across all scanners.
Developing a non-invasive ultrasound neuromodulation platform designed to engage the body’s anti-inflammatory neural pathways for treatment of chronic inflammatory disorders.
Developing EEG-enabled headphones delivering personalised, non-invasive neuromodulation and audio-based stimulation for mental health and cognitive enhancement.
Developing a non-invasive, AI-powered brain-computer interface (BCI) headset and proprietary neural-decoding platform to enable individuals with paralysis to control wheelchairs.
Developing the Stentrode, an endovascular, minimally invasive BCI implant enabling paralyzed individuals to control digital devices using thought alone.
Using 60 Hz non-invasive light stimulation via the eyes to trigger microglia-mediated neuroplasticity, offering a fast, drug-free option for depression and brain recovery.
Developing a wearable device for continuous cerebral blood flow monitoring, positioned around brain hemodynamics, performance, and broader brain health applications.
Building an organic computing platform that integrates living human neurons with modern AI architectures to improve model efficiency and discover novel computational algorithms.
Developing a wearable EEG patch that predicts epileptic seizures 30–60 minutes before onset, aiming to enable preventative intervention and safer independent living.
Developing a consumer-oriented, non-invasive brain stimulation device using amplitude-modulated transcranial pulsed random noise stimulation for cognitive enhancement.
Developing at-home photobiomodulation headsets and applicators that use near-infrared light to support cognitive enhancement, mood, sleep, and overall brain wellness.
Providing AI-powered EEG brain mapping software that enables point-of-care monitoring of dementia, correlating with amyloid, tau, atrophy, and cognitive endpoints.
Developing Cerebro, a minimally invasive endovascular brain access platform that enables treatment of neurological disorders without drilling through the skull.
Developing the Mudra wristband, a neural gesture recognition wearable that decodes hand and finger movement intent from neuromuscular signals for human-computer interaction.
Analyzing natural speech via tablet to extract vocal biomarkers that detect and monitor cognitive impairment, enabling objective, scalable assessments.
Developing soft, stretchable implantable electrodes that improve safety and performance of neuromodulation leads in neuromonitoring and neurostimulation.
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