Inside

Tools and Infrastructure

Foundational technologies, platforms,
and systems that enable the
development, deployment, and
scaling of neurotechnology by
supporting data capture, processing, analysis, and integration.
Explained
The tools and infrastructure layer of neurotechnology comprises the underlying software, hardware, and data systems that power the broader ecosystem. Rather than delivering end-user devices or therapies, these technologies operate behind the scenes, providing the pipelines, developer frameworks, and analytical foundations that other neurotech products rely on.

This layer spans a wide range of capabilities, including biosignal acquisition systems, edge and cloud-based signal processing, data management platforms, developer toolkits, and validation frameworks. By standardizing and abstracting complex technical components, infrastructure providers allow researchers, startups, and clinical teams to focus on application-specific innovation rather than rebuilding core systems from scratch.

Over the past decade, advances in low-power computing, machine learning, and cloud infrastructure have significantly expanded what these platforms can support. Real-time neural data processing at the edge, scalable multimodal data integration, and regulator-ready digital biomarkers have moved from experimental concepts into routine use across research and clinical development.

As neurotechnology matures, tools and infrastructure are increasingly recognized as a critical enabler of progress across brain–computer interfaces, neuromodulation, neuroimaging, and neurotherapeutics. Much like cloud and developer platforms in the broader tech sector, this layer is lowering barriers to entry, reducing technical and regulatory risk, and accelerating the translation of neuroscience into real-world products.
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Domains

Signal Acquisition & Preprocessing Platforms

Hardware and software systems that capture neural and physiological signals and perform initial amplification, filtering, and feature extraction. These platforms provide standardized, research- and clinic-ready data streams, enabling rapid experimentation without custom electronics development.

AI-Driven Biosignal Interpretation Platforms

Software and cloud platforms that apply machine learning to convert raw neural, physiological, or behavioral data into quantitative biomarkers. These systems are critical for clinical trials, diagnostics, and drug development, where scalable, validated interpretation of complex brain data is required.

Neuroimaging & Trial Data Management Platforms

Infrastructure designed to ingest, curate, analyze, and audit large-scale neuroimaging and digital biomarker datasets in regulated environments. These platforms support multi-site clinical trials and longitudinal studies, ensuring data quality, compliance, and reproducibility.

Closed-Loop Control & Neural Operating Systems

Real-time software stacks that manage sensing, decision-making, and stimulation in adaptive neurotech devices. These systems enable low-latency closed-loop operation, forming the control layer for advanced BCIs, neuromodulation systems, and neurofeedback applications.

Brain-on-Chip & Neurobiological Testing Platforms

In vitro platforms that combine neural tissue, organoids, or cultured neurons with high-density recording interfaces. These systems allow scalable, human-relevant testing of drugs, materials, and stimulation strategies, reducing reliance on animal models and accelerating discovery.

Neuromorphic Computing

Hardware and software platforms modeled on neural computation, including neuromorphic chips and living neural networks. These systems explore low-power, brain-inspired processing and provide experimental substrates for studying learning, adaptation, and intelligence.

Simulation & Digital Brain Modeling Engines

Computational platforms that model neural circuits, networks, or patient-specific brain dynamics in silico. Used for hypothesis testing, therapy planning, and device optimization, these tools are increasingly positioned as complements to physical trials.

Developer Kits, SDKs & Neuro-Aware Sensors

Modular hardware, APIs, and software tools that enable rapid prototyping of neurotech applications. By lowering technical barriers, these tools democratize experimentation across academia, startups, and adjacent industries such as XR, robotics, and digital health.
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Startups

Altoida

Providing a digital multimodal NeuroMarker platform to objectively assess and monitor cognitive function and detect early signs of neurodegenerative decline.
USA
Tools and Infrastructure

Machine Learning

Biomarkers

Arctop

Developing a hardware-agnostic brain-computer interface platform that decodes neural activity to deliver real-time cognitive and intention metrics via developer APIs and SDKs.
USA
Tools and Infrastructure

Machine Learning

Software

Aural Analytics

Delivering clinical-grade, non-invasive speech analytics to assess neurological health and monitor neurodegenerative diseases.
USA
Tools and Infrastructure

Software

Biomarkers

BIOS Health

Advancing precision medicine by interpreting the nervous system’s real-time data using AI-driven neural interfaces.
UK
Tools and Infrastructure

Diagnostics

Biomarkers

Beacon Biosignals

Accelerating precision neuroscience in clinical trials by capturing and analyzing sleep EEG with AI-powered biomarkers.
USA
Tools and Infrastructure

Biomarkers

Wearable

BioSerenity

Developing connected medical devices and digital health software for ambulatory EEG acquisition, remote diagnostics, and continuous monitoring in neurology and related conditions.
France
Tools and Infrastructure

Biomarkers

Non-invasive

BrainScope

Developing non-invasive EEG-based diagnostic devices to rapidly assess traumatic brain injury and support clinical decision-making at the point of care.
USA
Tools and Infrastructure

Diagnostics

Non-invasive

BrainTrip

Providing EEG-based brain mapping and neurofeedback software to support personalized assessment and training of brain function.
Slovenia
Tools and Infrastructure

Biomarkers

Diagnostics

Cambridge NeuroTech

Delivering high-channel-count silicon neural probes and ultra-small headstages enabling artifact-free electrophysiology and optogenetics.
UK
Tools and Infrastructure

Data Infrastructure

Research Tool

Ceribell

Developing rapid-response EEG systems and AI software to enable fast detection of seizures and status epilepticus at the point of care.
USA
Tools and Infrastructure

Diagnostics

Non-invasive

Clee Medical

Developing ultra-high-resolution intraoperative imaging with AI navigation to enable minimally invasive, precise brain surgery.
Switzerland
Tools and Infrastructure

Data Infrastructure

Machine Learning

Cogitat

Developing AI-driven EEG decoding software to enable device-agnostic brain-computer interaction and neural signal interpretation.
UK
Tools and Infrastructure

Machine Learning

Non-invasive

Cortical Labs

Developing the CL1 'biocomputer', a silicon-embedded, lab-grown neuron platform (SBI) that learns via real-time neural code execution.
Australia
Tools and Infrastructure

Data Infrastructure

Research Tool

Cumulus Neuroscience

Developing a wearable EEG and digital biomarker platform to enable remote, objective measurement of brain function in clinical trials and neuroscience research.
UK
Tools and Infrastructure

Biomarkers

Wearable

Empatica

Developing medical-grade wearable sensors and analytics to enable remote monitoring and detection of neurological and physiological events.
USA
Tools and Infrastructure

Wearable

Clinically Approved

Epihunter

Developing a wearable-based seizure detection system to monitor nocturnal epileptic seizures in children using passive physiological signals.
Belgium
Tools and Infrastructure

Wearable

Pediatric

Eysz

Developing eye-tracking–based neuroassessment software to objectively detect and monitor concussion and brain injury.
USA
Tools and Infrastructure

Diagnostics

Software

Firefly Neuroscience

Developing EEG-based brain network analytics software to support objective assessment of neurological and psychiatric conditions.
USA
Tools and Infrastructure

Diagnostics

Clinically Approved

Great Lakes NeuroTech

Developing EEG-based neuroimaging and brain-computer interface software for neuroscience research and clinical applications.
USA
Tools and Infrastructure

Research Tool

Software

Hume AI

Empowers AI with emotional intelligence, creating empathic speech capabilities and measuring nuance in voice, text, and facial expression.
USA
Tools and Infrastructure

Biomarkers

Software

Icometrix

Developing AI-powered neuroimaging software to quantify brain structures and pathology for clinical decision support and research.
Belgium
Tools and Infrastructure

Machine Learning

Diagnostics

Kandu

Developing a digital recovery platform to support stroke survivors through personalized guidance, monitoring, and coordinated post-acute care.
USA
Tools and Infrastructure

Rehabilitation

Software

Kernel

Providing fNIRS neuroimaging (Flow) for high-density brain monitoring targeting research and potential BCI applications in cognition and health.
USA
Tools and Infrastructure

Research Tool

Non-invasive

Kneu Health

Developing a wearable and software platform to monitor neurological function and recovery using objective movement and physiological data.
UK
Tools and Infrastructure

Rehabilitation

Wearable

Linus Health

Developing digital cognitive assessment and decision-support tools to enable earlier detection and management of neurodegenerative disease.
USA
Tools and Infrastructure

Diagnostics

Software

Machine Medicine

Providing AI-powered video assessment of Parkinson’s motor symptoms, offering objective, reproducible metrics for clinical trials and care.
UK
Tools and Infrastructure

Data Infrastructure

Biomarkers

MaxWell Biosystems

Delivering high-density microelectrode array platforms that record and stimulate neural cells in vitro, accelerating neuroscience and drug discovery.
Switzerland
Tools and Infrastructure

Data Infrastructure

Research Tool

MindRove

Offering wearable EEG and EMG biosensing devices and SDK for neural interface development, neurofeedback, rehabilitation, and research applications.
Hungary
Tools and Infrastructure

Data Infrastructure

Research Tool

Neurofenix

Developing a home-based neurorehabilitation system that combines motion sensing, serious games, and adaptive therapy for stroke recovery.
USA
Tools and Infrastructure

Rehabilitation

Non-invasive

Nimbus

Developing cloud-native infrastructure and APIs that enable brain-computer interface developers to collect, train, and deploy neural data applications securely and at scale.
Netherlands
Tools and Infrastructure

Data Infrastructure

Research Tool

Oculogica

Developing eye-tracking–based neuroassessment software to objectively detect and monitor concussion and traumatic brain injury.
USA
Tools and Infrastructure

Diagnostics

Non-invasive

Open Neurotech

Building open-source neurotechnology tools and standards that make advanced brain-computer interfaces accessible to researchers, developers, and creators worldwide.
USA
Tools and Infrastructure

Data Infrastructure

Research Tool

OpenBCI

Open-source biosensing hardware (EEG/EMG/EKG) and Galea (EEG+biometrics for XR) for BCI research and developer tools.
USA
Tools and Infrastructure

Data Infrastructure

Research Tool

Pison Technology

Developing a wearable neural sensing platform that uses peripheral nerve signals to enable cognitive monitoring and human–computer interaction.
USA
Tools and Infrastructure

Wearable

Machine Learning

Prima Mente

Developing biological foundation models and clinical research platforms to understand, detect, and prevent neurological disease through AI-driven neuroscience.
UK
Tools and Infrastructure

Machine Learning

Research Tool

Purple Gaze

Developing eye-tracking–based assessment software to support early screening and monitoring of neurodevelopmental conditions.
Netherlands
Tools and Infrastructure

Non-invasive

Diagnostics

QMENTA

Empowering imaging teams with a cloud-native AI platform that automates MRI data upload, biomarker extraction, and centralized review for clinical trials.
USA
Tools and Infrastructure

Machine Learning

Biomarkers

RetiSpec

Developing retinal imaging and AI software to detect neurodegenerative disease by analyzing biomarkers in the eye.
Canada
Tools and Infrastructure

Diagnostics

Biomarkers

Sense Neuro Diagnostics

Developing a non-invasive neurodiagnostic system to objectively assess concussion and brain injury using advanced brain signal analysis.
USA
Tools and Infrastructure

Diagnostics

Non-invasive

Sensome

Developing Clotild, a smart guidewire using impedance-based microsensors and AI to characterize vascular tissue and aid intraoperative decision-making in stroke treatment.
France
Tools and Infrastructure

Diagnostics

Implantable

Sevaro

Delivering virtual neurology services and tele-neurology programs to provide rapid, specialized neurological care to hospitals.
USA
Tools and Infrastructure

Software

Diagnostics

Synchroni

Building infrastructure for neurotech apps, enabling non-invasive neural data capture, training, and deployment.
USA
Tools and Infrastructure

Data Infrastructure

Software

Vonova

Developing Cerebro, a minimally invasive endovascular brain access platform that enables treatment of neurological disorders without drilling through the skull.
USA
Tools and Infrastructure

Implantable

Research Tool

Yneuro

Developing neural authentication software that uses unique neural signatures as a biometric for secure digital identity and access.
France
Tools and Infrastructure

Experimental

Biomarkers