The Biological Computing Company (TBC) is a San Francisco-based startup building an organic computing platform that integrates living human neurons with modern AI architectures. Founded in 2022 by neurosurgeon-neuroscientists Alex Ksendzovsky and Jon Pomeraniec (formerly Biological Black Box), the company raised $25 million in seed funding led by Primary Ventures in February 2026.

TBC's neuroscience and engineering team encodes real-world data (images, video, text) into living neurons cultured on electrode grids, then decodes the resulting neural activity patterns into richer data representations that are mapped onto frontier AI models through modular adapters. In parallel, the company's Algorithm Discovery platform extracts computational principles from living neural networks to inform the design of novel AI architectures beyond transformers. The company reports a 23x retained improvement in video model efficiency using its biological adapters.

TBC targets the AI infrastructure market, positioning biological computing as a new layer of compute that strengthens existing architectures rather than replacing silicon. The company's thesis is that neurons offer advantages in continuous learning, pattern extraction from sparse data, and energy efficiency. TBC has opened a flagship lab in San Francisco's Mission Bay for customer deployment, with a stated 10-to-20-year roadmap for integrating biological networks into real-time compute circuits.