Inside

Neuroimaging

Technologies that measure, visualize, or infer brain structure and activity using physical, electrical, optical, or molecular signals to support research, diagnosis, and therapeutic development.
Explained
Neuroimaging encompasses a broad set of techniques used to observe the brain’s structure, function, and physiology, either directly or through indirect biological signals. These technologies make it possible to study how the brain is organized, how it changes over time, and how neural activity relates to behavior, disease, and treatment response.

Imaging modalities vary widely in what they measure and how they operate, ranging from structural approaches such as MRI to functional and physiological techniques including fMRI, EEG, fNIRS, PET, and emerging ultrasound-based methods. Each modality involves trade-offs across spatial resolution, temporal resolution, invasiveness, cost, and portability, shaping where and how it can be deployed.

Historically, neuroimaging has been central to clinical neurology and neuroscience research, supporting diagnosis, disease monitoring, and functional brain mapping. More recently, advances in hardware miniaturization and computational analysis have expanded neuroimaging beyond the hospital, enabling wearable, point-of-care, and longitudinal brain monitoring in more naturalistic settings.

As the field evolves, neuroimaging is increasingly defined not by individual modalities, but by multimodal and AI-enhanced approaches that combine complementary data sources to extract actionable insights. Rather than serving as a single diagnostic tool, neuroimaging is becoming a foundational layer for biomarker discovery, precision medicine, and the development of brain-based technologies across healthcare and research.
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Modalities

MRI (Magnetic Resonance Imaging)

A non-invasive imaging technique that uses strong magnetic fields and radiofrequency pulses to generate high-resolution images of brain anatomy. MRI provides detailed structural information and is the clinical gold standard for detecting lesions, atrophy, vascular abnormalities, and neurodegenerative changes.

fMRI (Functional MRI)

A functional extension of MRI that measures blood-oxygen-level–dependent (BOLD) signals to infer neural activity. fMRI enables whole-brain mapping of functional networks and task-related activation, but is limited by indirect hemodynamic signals and relatively slow temporal resolution.

EEG (Electroencephalography)

A technique that records electrical brain activity from electrodes placed on the scalp, capturing neural dynamics with millisecond temporal resolution. EEG is widely used in clinical diagnostics and research, though spatial resolution is limited due to signal distortion through the skull and scalp.

fNIRS (functional Near-Infrared Spectroscopy)

An optical neuroimaging method that measures changes in cortical blood oxygenation using near-infrared light. fNIRS offers moderate spatial resolution and improved portability compared to MRI, but is limited to superficial cortical regions and slower hemodynamic responses.

MEG (Magnetoencephalography)

A modality that detects magnetic fields generated by synchronized neuronal currents, providing real-time measurement of brain activity. MEG offers temporal resolution comparable to EEG with improved source localization, but remains costly and hardware-intensive, with wearable systems still emerging.

PET / SPECT (Molecular Neuroimaging)

Nuclear imaging techniques that use radioactive tracers to visualize brain metabolism, perfusion, or specific molecular targets. PET and SPECT are critical for studying neurodegenerative disease, epilepsy, and oncology, but involve radiation exposure and lack real-time temporal resolution.

Functional Ultrasound (fUS)

An emerging imaging approach that maps neural activity by detecting high-resolution changes in cerebral blood flow using ultrafast ultrasound. fUS offers promising spatial and temporal resolution with relatively portable hardware, but remains early in clinical validation and often requires specialized acoustic access.

Multimodal & AI-Enhanced Imaging

Integrated approaches that combine multiple imaging modalities and apply machine-learning models to improve interpretation and clinical utility. These systems aim to overcome individual modality limitations by fusing structural, functional, and physiological data into unified brain assessments.
Articles
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Startups

Axon Interfaces

Empowering frontline EEG systems by transforming raw brain data into real-time, AI-powered clinical biomarkers.
USA
Neuroimaging

Biomarkers

Machine Learning

Bitbrain

Empowering multimodal brain–body research with wearable EEG and biosensor systems, backed by AI-powered data platforms.
Spain
Neuroimaging

Biomarkers

Machine Learning

BrainCapture

Expanding access to neurological diagnostics by deploying portable EEG systems and telemedicine tools for remote epilepsy detection.
Denmark
Neuroimaging

Data Infrastructure

Biomarkers

BrainKey

Visualizing users' MRI scans in 3D and delivers personalized brain health insights-including brain age and lifestyle recommendations.
USA
Neuroimaging

Biomarkers

Machine Learning

BrainSightAI

Generating personalized, AI-based connectome maps from MRI (VoxelBox) to support surgical planning and psychiatric diagnostics.
India
Neuroimaging

Diagnostics

Machine Learning

Brainomix

Developing AI-driven neuroimaging software to support rapid, standardized analysis of brain scans for stroke and other neurological conditions.
UK
Neuroimaging

Diagnostics

Machine Learning

Cercare Medical

Transforming CT and MRI scans into fully automated perfusion maps and advanced microvascular biomarkers to guide stroke and neuro-oncology care.
Denmark
Neuroimaging

Data Infrastructure

Diagnostics

Cerebriu

Delivering real-time AI-driven MRI workflows, detecting brain infarcts, hemorrhages, and tumors mid-scan to adapt protocols and prioritize urgent cases.
Denmark
Neuroimaging

Data Infrastructure

Diagnostics

CoMind

Developing a non-invasive infrared-based brain monitoring system to provide real-time cerebral perfusion, autoregulation, and intracranial pressure insights in critical care.
UK
Neuroimaging

Diagnostics

Non-invasive

Cognision

Providing an FDA-cleared portable ERP/EEG system for objective assessment of cognitive impairment in dementia, concussion, and TBI.
USA
Neuroimaging

Diagnostics

Clinically Approved

Cordance Medical

Developing a non-invasive focused ultrasound platform to precisely open the blood–brain barrier and enable targeted drug delivery and brain diagnostics.
USA
Neuroimaging

Experimental

Non-invasive

CortiVision

Enabling mobile, high-density fNIRS brain imaging, used from labs to the ISS, tracking brain activity via oxygenation, multimodal interactions, and hyperscanning.
Poland
Neuroimaging

Biomarkers

Diagnostics

DEEGtal

Delivering an AI-driven platform that enhances traditional EEG analysis by uncovering complex, visually silent patterns, enabling faster, more accurate epilepsy diagnoses.
Switzerland
Neuroimaging

Biomarkers

Diagnostics

DeepSpin

Building portable, affordable AI-powered MRI systems, delivering high-quality brain imaging at 20× lower cost, weight, and infrastructure needs.
Germany
Neuroimaging

Research Tool

Machine Learning

ELDA BrainTech

Combining MRI-compatible EEG cap with AI to pinpoint epileptic zones via simultaneous EEG–fMRI recordings, improving diagnosis precision.
Israel
Neuroimaging

Diagnostics

Machine Learning

EMOTIV

Offering wireless, multi-channel EEG headsets and SDKs, empowering BCI research, emotion tracking, and hands-free control across diverse applications.
USA
Neuroimaging

Wearable

Research Tool

EMVision

Developing portable electromagnetic brain imaging systems to enable rapid, point-of-care diagnosis of stroke and other acute neurological conditions.
Australia
Neuroimaging

Diagnostics

Non-invasive

Epiminder

Developing an implantable seizure monitoring system to provide continuous, objective tracking of epileptic activity over long durations.
Australia
Neuroimaging

Implantable

Diagnostics

Epitel

Developing wearable, long-term EEG monitoring systems to enable continuous seizure detection and neurological assessment outside the hospital.
USA
Neuroimaging
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Gowerlabs

Delivering wearable, high-density fNIRS systems (LUMO & NTS) for 3D brain imaging in infants and adults across research and clinical settings globally.
UK
Neuroimaging

Pediatric

Experimental

ICONEUS

Developing functional ultrasound neuroimaging systems to enable high-resolution, real-time imaging of brain activity in research and clinical settings.
France
Neuroimaging

Non-invasive

Research Tool

IDUN Technologies

Developing discreet in-ear EEG sensors and neuroanalytics to transform everyday wearables into continuous brain-state monitoring tools.
Switzerland
Neuroimaging

Wearable

Research Tool

Imeka

Developing AI-driven neuroimaging software to analyze diffusion MRI data for improved diagnosis and monitoring of neurological disorders.
USA
Neuroimaging

Machine Learning

Biomarkers

Longeviti Neuro Solutions

Developing ultrasound-based neuroimaging platforms to enable real-time brain imaging during and after complex neurosurgical procedures.
USA
Neuroimaging

Non-invasive

Diagnostics

Magnetic Insight

Developing Magnetic Particle Imaging (MPI) systems enabling high-sensitivity preclinical imaging and advancing into clinical diagnostics.
USA
Neuroimaging

Diagnostics

Software

NeuraLight

Extracting eye-movement biomarkers via AI and computer vision from standard webcams or smartphones to accelerate CNS drug development and neurology diagnostics.
Israel
Neuroimaging

Biomarkers

Machine Learning

Neuro42

Building FDA-cleared portable, robotic and AI-driven MRI platforms that bring real-time neuroimaging and interventional guidance directly to patients.
USA
Neuroimaging

Diagnostics

Clinically Approved

NeuroBell

Providing pocket‑sized, AI‑powered wireless EEG monitoring that detects neonatal seizures at the NICU bedside for early intervention.
Ireland
Neuroimaging

Pediatric

Machine Learning

Neuronostics

Applying AI and mathematical modeling to EEG data to generate rapid, digital biomarkers that pinpoint seizure risk and support epilepsy diagnosis.
UK
Neuroimaging

Diagnostics

Machine Learning

Neurophet

Developing AI-driven neuroimaging software to analyze brain MRI scans for early detection and monitoring of neurodegenerative diseases.
South Korea
Neuroimaging

Machine Learning

Diagnostics

Neurosteer

Equipping clinicians with a wearable, medical-grade EEG system that delivers real-time neural biomarkers via a head-adhered sensor and cloud analytics.
USA
Neuroimaging

Wearable

Diagnostics

Optohive

Offering wearable fNIRS brain imaging (HiveOne + AI software) for real-time, high-precision neural monitoring in clinical and research settings.
Switzerland
Neuroimaging

Diagnostics

Machine Learning

PIXYL

Applying FDA-cleared, AI-powered analysis to brain MRI scans, enabling rapid lesion detection and volumetric quantification for neurological care.
France
Neuroimaging

Clinically Approved

Software

Resolve Stroke

Developing software-based ultrasound neuroimaging systems to extract advanced brain biomarkers from raw ultrasound data for bedside monitoring.
France
Neuroimaging

Biomarkers

Software

Subtle Medical

Providing AI-powered enhancements for MRI and PET scanning, boosting image clarity, reducing scan time, and enabling dose minimization across all scanners.
USA
Neuroimaging

Machine Learning

Software

UNEEG Medical

Developing implantable, long-term EEG monitoring systems to enable continuous brain activity recording for epilepsy management.
Denmark
Neuroimaging

Diagnostics

Implantable

ViewMind

Enabling non-invasive, VR headset-based assessment of neurocognitive health using eye movement biomarkers with high sensitivity and specificity.
USA
Neuroimaging

Diagnostics

Biomarkers

X-trodes

Developing rapid-application dry EEG electrode systems to enable high-quality brain signal acquisition without gels or skin preparation.
Israel
Neuroimaging

Research Tool

Non-invasive