STARTUP PROFILE

SetPoint Medical

COUNTRY
USA
FOUNDED
2006
CATEGORY
Neuromodulation
Developing an implantable vagus nerve stimulation system for rheumatoid arthritis through neuroimmune modulation of inflammatory pathways.
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Neurofounders Insights
$   Funding   -
Series C+
MODALITY
VNS
FORM FACTOR
Implant
INTERFACE DEPTH
Implantable
INDICATION
Other
TARGET USER
Patients
REGULATORY STAGE
FDA approved (PMA)
SetPoint Medical sits in one of the more clinically advanced areas of bioelectronic medicine, using implantable VNS to modulate inflammatory pathways in rheumatoid arthritis. Its positioning is notable because it places neuromodulation inside immune-mediated disease, expanding the category beyond conventional neurological applications.
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Mentioned in Market Notes
MOST RECENT COVERAGE
#
10
Neurotech Has Arrived
15 September – 29 September 2026

SetPoint Medical's system reached patients in Southern New Jersey, where the Global Neurosciences Institute performed its first procedures for rheumatoid arthritis. SetPoint's implant, the first FDA-approved neuroimmune modulation therapy, stimulates the vagus nerve to activate anti-inflammatory pathways.

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