Arboretum Ventures is a venture capital firm based in Ann Arbor that focuses on medical devices, life science tools, diagnostics, and technology-enabled healthcare delivery. The firm is known for backing capital-efficient healthcare companies, particularly outside the most crowded US coastal venture markets.

Its neurotech-related portfolio includes companies such as Motif Neurotech, Pharaoh Neuro, and Avation Medical, reflecting clear interest in neuromodulation and neurodevice innovation. Arboretum tends to favor technologies with practical clinical applications and identifiable regulatory paths.

The firm’s geographic focus is primarily the United States, with particular strength in overlooked innovation hubs. It is especially relevant for neurotech founders building medical devices with clear clinical utility and a realistic path to commercial adoption.