Fifty Years is a San Francisco-based venture capital firm that invests in early-stage companies solving major global problems through science and technology. The fund is mission-driven and has become well known for backing technically ambitious startups before they are broadly recognized by the market.

Its portfolio includes companies in deep tech, biology, food systems, and health, including neuro-relevant businesses such as BIOS Health. The firm also supports founders through venture-building and scientist-to-founder transition programs, which makes it especially useful for technically strong but first-time entrepreneurial teams.

Fifty Years invests globally, with strongest presence in North America and Europe. It is especially relevant for neurotech companies that are early, technically bold, and motivated by transformative impact rather than incremental healthcare optimization.