Glossary

A structured index of terms that appear across the neurotech landscape and in Neurofounders' reporting.​

600+ Terms  ●  Reviewed often  ●  Growing monthly

<- Back
Filter by category
Filter by tag
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Clear
<- Back

Co-adaptive training protocols

Training methods where both user strategies and decoder parameters adapt continuously.
Brain-Computer Interface

Code repository

Central store for source code and related files, often integrated with collaboration and CI/CD tools.
Tools and Infrastructure

Cognitive assessment battery

A set of tests covering multiple cognitive domains (e.g., memory, attention, executive function).
Cognitive and Mental Health

Cognitive behavioral therapy (CBT)

A structured psychotherapy focused on modifying unhelpful thoughts and behaviors to improve mood and functioning.
Cognitive and Mental Health

Cognitive flexibility

The capacity to switch between tasks, strategies, or mental sets in response to changing demands.
Cognitive and Mental Health

Cognitive load

The total mental effort required to perform a task or handle information at a given moment.
Cognitive and Mental Health

Cognitive reframing

Restructuring unhelpful thoughts to reduce distress or improve functioning.
Cognitive and Mental Health

Cognitive resilience

Ability to maintain cognitive performance despite stress, fatigue, or age-related changes.
Cognitive and Mental Health

Cognitive state decoding

Inferring internal states such as workload, attention, or intention from neural signals.
Cognitive and Mental Health

Cognitive vulnerability

Patterns of thinking that make a person more susceptible to depression or anxiety.
Cognitive and Mental Health

Cognitive workload model

Framework estimating mental effort from task metrics or physiology.
General

Cognitive workload monitoring

BCIs estimating mental effort from neural signals to adapt interfaces or tasks.
Brain-Computer Interface

Command set

The set of actions available through a BCI (e.g., left, right, select).
Brain-Computer Interface

Common average reference (CAR)

Referencing scheme that subtracts the average of all channels from each channel to reduce shared noise.
Tools and Infrastructure

Common-mode rejection ratio (CMRR)

Measure of how well an amplifier suppresses noise common to all input channels.
Tools and Infrastructure

Compulsivity

Repetitive, difficult-to-control behaviors driven by urges rather than goals.
Cognitive and Mental Health

Computational neuroscience model

Mathematical model describing neural dynamics or network behavior.
General

Computed tomography (CT)

X-ray-based imaging that reconstructs cross-sectional brain images, often used in acute clinical settings.
Neuroimaging

Conductive gel

Gel applied between electrodes and skin to reduce impedance and improve current delivery.
Neuromodulation

Cone-beam CT

A CT variant using a cone-shaped X-ray beam, often applied in head and neck or interventional contexts.
Neuroimaging

Connectome

A comprehensive map of structural or functional connections between brain regions.
Neuroimaging

Connectomic targeting

Selecting stimulation sites based on network connectivity rather than only anatomy.
Neuromodulation

Contact impedance

The electrical resistance at the electrode–tissue interface, affecting stimulation efficiency.
Neuromodulation

Containerization

Packaging code and dependencies into isolated units (e.g., Docker containers) for reproducible deployments.
Tools and Infrastructure

Context-aware decoding

Decoding that integrates neural data with task or environmental context to improve accuracy.
Brain-Computer Interface

Continuous TBS (cTBS)

TBS pattern typically associated with net inhibitory effects on cortical excitability.
Neuromodulation

Continuous integration / continuous deployment (CI/CD)

Automated pipelines that test, build, and deploy code or models when changes are made.
Tools and Infrastructure

Control signal

A neural feature mapped to a specific BCI command or output.
Brain-Computer Interface

Cortical excitability

The ease with which cortical neurons can be activated, often modulated by stimulation protocols.
Neuromodulation

Cortical thickness

The distance between the white and pial surfaces of cortex, often used as a marker of structural integrity.
Neuroimaging

Cranial electrotherapy stimulation (CES)

Low-intensity electrical stimulation applied via ear clips or scalp to modulate mood or sleep.
Neuromodulation

Cross-frequency coupling

Interaction between neural oscillations at different frequencies, sometimes used as a control feature in BCIs.
Brain-Computer Interface

Cross-validation

Technique splitting data into subsets to estimate model generalizability.
Tools and Infrastructure

Crosstalk (neural recording)

Unwanted interference between recording channels or nearby electrodes.
Brain-Computer Interface

Current steering

Shaping current flow through multiple electrodes to focus or shift stimulation effects.
Neuromodulation

Cursor control BCI

Systems enabling cursor movement through decoded neural activity.
Brain-Computer Interface

Cybersecurity hardening (medical devices)

Enhancing device security to prevent breaches, tampering, or unauthorized data access.
General

Dashboard

Visual interface that aggregates metrics, trends, and alerts for monitoring systems or cohorts.
Tools and Infrastructure

Data acquisition system (DAQ)

Hardware-software stack that records biosignals (e.g., EEG, fNIRS, EMG) and streams them to a computer in real time.
Tools and Infrastructure

Data annotation protocol

Standardized rules for labeling signals, images, or behaviors consistently.
General

Data dictionary

Structured reference defining variables, units, formats, and permissible values.
Tools and Infrastructure

Data governance

Policies and processes that define how data is collected, stored, accessed, and used responsibly.
Tools and Infrastructure

Data harmonization

Processes that standardize datasets collected across devices, protocols, or study sites.
Tools and Infrastructure

Data ingestion service

Software that receives, validates, and routes incoming data streams from devices or APIs.
Tools and Infrastructure

Data lake

Large storage repository that holds raw, heterogeneous data (signals, logs, metadata) at scale.
Tools and Infrastructure

Data lifecycle management

Governance of data from collection through storage to deletion.
General

Data pipeline

End-to-end process that moves data from acquisition through cleaning, transformation, and storage.
Tools and Infrastructure

Data provenance

Documentation of where data came from and how it was processed across its lifecycle.
Tools and Infrastructure

Data pseudonymisation

The process of replacing personal identifiers with coded substitutes so data can be linked without revealing identity, while still allowing re-identification under controlled conditions.
Tools and Infrastructure

Data quality checks

Automated or manual tests verifying completeness, consistency, and validity of data.
Tools and Infrastructure

Data warehouse

Centralized, structured database optimized for analytics and reporting on curated datasets.
Tools and Infrastructure

De Novo classification

FDA pathway for first-of-kind devices with no predicate but low-to-moderate risk.
General

De-identification

Broad process of removing or generalizing personal identifiers to reduce privacy risk.
Tools and Infrastructure

Decoder calibration

Collecting training data to optimize BCI decoding performance.
Brain-Computer Interface

Decoder drift

Gradual changes in neural signal properties that reduce decoding accuracy unless updated.
Brain-Computer Interface

Decoding analysis (neuroimaging)

Using machine learning to predict stimuli, tasks, or states from brain activity patterns.
Neuroimaging

Deep TMS

TMS using specialized coils (e.g., H-coils) designed to reach deeper brain structures.
Neuromodulation

Deep brain stimulation (DBS)

Invasive neuromodulation using implanted electrodes in deep brain structures, typically driven by a subcutaneous stimulator.
Neuromodulation

Default mode network (DMN)

A large-scale brain network active at rest and deactivated during many goal-directed tasks.
Neuroimaging

Delta band (δ)

Slow brain oscillations typically around 0.5–4 Hz, prominent in deep sleep and some pathological states.
Neuroimaging

Delusion

Fixed, false belief not aligned with cultural norms and resistant to contradictory evidence.
Cognitive and Mental Health

Dementia

A syndrome of substantial cognitive decline that interferes with daily functioning, often progressive.
Cognitive and Mental Health

Deployment environment

The computational and physical setting where a system runs (clinic, cloud, OR, wearable).
General

Desensitization (neuromodulation)

Reduced responsiveness to repeated stimulation, requiring parameter adjustment.
Neuromodulation

Device artifact

Signal distortion introduced by hardware or electrical interference.
General

Device calibration

Procedure ensuring a device’s measurements remain accurate.
General

Device firmware

Embedded software running directly on neurotech hardware.
Tools and Infrastructure

Device lifecycle management

Coordinated oversight of versioning, maintenance, updates, and retirement of devices.
General

Diffuse optical tomography (DOT)

Optical imaging method reconstructing 3D maps of cortical hemodynamics using near-infrared light.
Neuroimaging

Diffusion tensor imaging (DTI)

A diffusion MRI method that models directional water diffusion to infer white matter pathways.
Neuroimaging

Diffusion-weighted imaging (DWI)

MRI technique measuring the diffusion of water molecules, sensitive to microstructural changes and acute stroke.
Neuroimaging

Digital biomarker

A quantifiable behavioral or physiological signal measured by digital tools that relates to health or disease.
Cognitive and Mental Health

Digital biomarker platform

Infrastructure that ingests sensor data, extracts features, and computes clinically relevant metrics.
Tools and Infrastructure

Digital cognitive biomarker

Behavioral or sensor-derived metric that reflects cognitive function in everyday environments.
Cognitive and Mental Health

Digital endpoint

A clinically meaningful metric derived from sensor data in trials or remote monitoring.
General

Digital health

Technology-enabled healthcare including apps, sensors, telehealth, and analytics.
General

Digital phenotyping engine

System extracting behavioral and physiological markers from continuous sensor data.
Tools and Infrastructure

Digital therapeutic

Software-based intervention with demonstrated clinical benefit, often delivered via apps or online platforms.
Cognitive and Mental Health

Digital twin (neural)

Computational model simulating a person’s neural system for prediction or personalization.
General

Directional lead

A stimulation lead with segmented contacts that steer current toward specific tissue regions.
Neuromodulation

Distributed computing framework

Infrastructure enabling parallel processing across multiple machines or clusters.
Tools and Infrastructure

Domain adaptation

ML methods aligning data distributions across subjects, sessions, or devices to improve generalization.
Tools and Infrastructure

Dorsal root ganglion stimulation (DRG stimulation)

Stimulation of dorsal root ganglia to modulate sensory pathways and chronic pain.
Neuromodulation

Dose (neuromodulation)

The combination of parameters (intensity, frequency, duration, number of sessions) defining a stimulation regimen.
Neuromodulation

Dose optimization

Systematic adjustment of stimulation or therapy parameters to maximize benefit.
Neuromodulation

Dose-response curve

Relationship between stimulation intensity/duration and physiological or behavioral effects.
Neuromodulation

Double-blind trial

A study design in which neither participants nor investigators know which intervention each participant receives, reducing expectancy and observer bias.
General

Drift correction

Adjustment applied when sensors or baselines shift slowly over time.
Tools and Infrastructure

Duty cycle

The proportion of time stimulation is “on” versus “off” within a given period.
Neuromodulation

Dysphoria

A state of unease or dissatisfaction, often used to describe negative mood.
Cognitive and Mental Health

ETL / ELT pipeline

Extract-Transform-Load (or Load-Transform) workflow that ingests raw data and prepares it for analysis.
Tools and Infrastructure

Echo planar imaging (EPI)

Fast MRI acquisition method commonly used in fMRI and diffusion imaging.
Neuroimaging

Echo time (TE)

The time between excitation and signal readout, influencing MRI contrast.
Neuroimaging

Ecological momentary assessment (EMA)

Repeated, in-the-moment data collection in real-world settings via phones or wearables.
Cognitive and Mental Health

Edge AI

Running neural network inference directly on devices (e.g., wearables, implants) instead of cloud.
Tools and Infrastructure

Edge computing

Running inference or preprocessing on-device or near the sensor, rather than in the cloud.
Tools and Infrastructure

Edge-secure firmware

Cryptographically protected firmware on clinical devices to prevent tampering and unauthorized updates.
General

Edge-to-cloud architecture

Workflow distributing processing between local devices and cloud systems.
General

Effective connectivity

Directional influence one brain region exerts over another, often inferred with causal models.
Neuroimaging

Electrocardiography (ECG/EKG)

Measurement of cardiac electrical activity, often synchronized with neural recordings.
Tools and Infrastructure

No results found